There are five types of diabetes not two, say scientists

Posted March 04, 2018

Leif Groop, one of the researchers, was quoted by BBC as saying.

The researchers identified five replicable clusters of patients with diabetes.

Scientists say diabetes is five separate diseases, and treatment could be custom fitted to each frame.

The other severe category, called severe insulin-resistant diabetes, is linked to obesity and shows a strong tendency for the body's cells not to respond to insulin, with these patients showing the highest likelihood of having liver disease, chronic kidney disease, and diabetic kidney disease. It is usually diagnosed in childhood and is caused by the body's immune system wrongly destroying cells in the pancreas that make insulin.

Diabetes is now divided into two major groups - Type-1 diabetes which accounts for around 10 per cent of the cases and Type-2 diabetes which accounts for 85-90 per cent of the cases.

Stemming from the All New Diabetics in Scania cohort, 8,980 Swedish patients newly diagnosed with diabetes were included in the hierarchical clustering.

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Diabetes is now divided into type 1 diabetes (approximately 10%), type 2 diabetes (85-90%) and several less common diseases like latent autoimmune diabetes in adults (LADA), maturity onset diabetes of the young (MODY) and secondary diabetes.

Cluster 2: This group consists of relatively young, insulin-deficient individuals with high blood sugar levels, faulty insulin secretion and moderate insulin resistance.

Thus, the need for new and better treatment options is great, Lund University said in a statement.

Dr Emily Burns from Diabetes UK said: "Much more research is needed before we'll know if this arthritis drug could be used to help people with Type 2 diabetes to manage their condition in the future".

"To support people to maintain a healthy weight and be more active, Bradford City and Bradford District Clinical Commissioning Groups (CCGs) are offering people at significant risk of diabetes across Bradford a place on the new NHS diabetes prevention programme". Without insulin, the body is unable to regulate blood sugar levels.

The six metrics used in the study include age at diagnosis, BMI, the presence of certain antibodies linked to autoimmune diabetes, insulin sensitivity measures and blood glucose control measures. I only have to look at my mum's workload to see that: as a diabetes specialist nurse, she's busier than ever, supporting patients throughout day to day management of their condition and some of the more serious complications of the disease, from blindness to kidney failure and limb amputation. The authors speculated that these patients would benefit most from Metformin.

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Furthermore, maybe their treatment should all the more intently reflect patients who are right now classed as type 1.

The researchers are also planning to launch similar studies in China and India with people of different ethnic backgrounds.

Mild obesity-related diabetes (MOD): characterised by obesity but not insulin resistance.

Each cluster has different risks associated with it, and patients could respond better to different treatments, researchers say.

The researchers, led by experts at Lund University, last night said the findings should prompt a "paradigm shift" in the way people treat diabetes.

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