In a series of social media posts, Ganguly wrote, "To see nearly 500 runs scored in 50 overs in England is scaring me, bout the health of the game and where it's going".
Eoin Morgan returns to the England side at the expense of Sam Billings. But the back-to-back dismissals of Morgan and Hales thwarted those ambitions and slowed down England innings a bit in the final few overs.
That is 38 more than the 443-3 they scored at the same ground two years ago, when Pakistan were the opponents, and is the latest statement of intent from the favourites for next year's World Cup.
On a day to forget for the bowlers, Richardson had the best figures, finishing with 3-92, who found himself on a hat-trick with the wickets of Hales and Morgan (67).More news: Time magazine cover puts Trump face to face with crying immigrant girl
A crestfallen Tim Paine admitted Australia's record 242-run defeat to England at Trent Bridge was the toughest day of his cricketing career.
In reply, Australia were dismissed to 239 runs in 37 overs to give England yet another bilateral ODI series win.
"That was the hardest day I've had in 16-17 years (of cricket)", skipper Tim Paine said.
During the course of the innings, Morgan also became the highest run-scorer for England in one-dayers.More news: 'Embarrassed' Mickelson apologises for U.S. Open rules violation
Bairstow is only the eighth player to score four centuries in six ODI innings, after Virat Kohli, David Warner, Quinton de Kock, Kumar Sangakkara, Hashim Amla, AB de Villiers and Zaheer Abbas.
"Everything we tried didn't work and everything they tried came off. Normally that happens for an hour or two and you get a wicket".
In the meantime, the Barmy Army also plundered the highest ever ODI score of 481 runs.
The five-match ODI tour, which will be followed by a solitary T20 worldwide, was meant to be a rebuilding exercise for the Australians.
There was no moment of respite for Australia bowlers after they asked England to bat first. Australia called for a review when they thought they detected an inside edge on one from Stanlake that nipped back at Roy (replays showed the ball brushed his trousers), while Bairstow was dropped on 30 by Marcus Stoinis running back from mid-off and reprieved on review having been given out leg before attempting to sweep Ashton Agar. In 20-overs cricket you can get away with it as it's more condensed, but in 50 overs you have a lot more time in the game than you think.More news: Sepp Blatter Thinks UK And Ireland Could Host 2030 World Cup